Fig. 4

Kaplan-Meier curves of survivals according to the four-bacteria signature. A–C Disease-free survival (DFS), distant metastasis-free survival (DMFS), and overall survival (OS) in the training cohort (n=171). D–F DFS, DMFS, and OS in the internal validation cohort (n=172). G–I DFS, DMFS, and OS in the external validation cohort (n=148). We calculated the P values using the unadjusted log-rank test and the hazard ratios using univariate Cox regression analysis