Fig. 3

Muribaculaceae and gut bacterial alpha-amylase genes are more abundant in mouse strains with low-amylase gene copy numbers. A Phylogenetic relationship among the six mouse strains tested, C57BL/6 J (B6), A/J (A/J), 129S1/SvImJ (129), NOD/ShiLtJ (NOD), NZO/HLtJ (NZO), and CAST/EiJ (CAST). B Amylase gene (Amy1 and Amy2) copy number in the six mouse strains. C Relative abundance of Muribaculaceae family across the six mouse strains fed a high carbohydrate diet and its correlation with host amylase gene copy number. D Relative abundance of gut bacterial alpha-amylase gene (K07405) across the six mouse strains and its correlation with host amylase gene copy number. Statistical difference among groups was tested by unpaired two-tailed Wilcoxon signed-rank test