Fig. 3

Community structure of colonic microbiome in 8-day-old and 90-day-old pigs administrated with or without PDCoV. A Venn diagram of shared OTUs based on the sequences with more than 97% similarity (n = 3), 8-day-old (left) and 90-day-old pigs (right). B The alpha diversity indexes (Chao1, Shannon, and Simpson) of the colonic microbiota in 8-day-old (left) and 90-day-old pigs (right). C Principal coordinate analysis (PCoA) of the colonic microbiota based on the weighted unifrac in 8-day-old (left) and 90-day-old pigs (right). D The hierarchical clustering analysis of the colonic microbiota. The panel on the left is a hierarchical clustering tree. The composition of the two samples is similar when the branch length between the samples is shorter. *p < 0.05; **p 0.01