Fig. 8

PC regulates intestinal cell abundance and rescues a large number of epithelial cells during infection. a Single-cell sequencing analysis of intestinal cell distribution after PC treatment; dimensionality reduction analysis using the t-SNE algorithm. b Expression analysis of cell markers in different cell groups. c Integrated map of the location and markers of various cell types in piglets. d Volcano plot and heatmap analysis of marker genes in different cell groups, with P ≤ 0.01 and gene expression fold change logFC ≥ 0.26. e Analysis of cell proportions in the PEDV and PC + PEDV groups. f Screening of highly expressed genes in early and late phases in intestinal cell groups. Panel c was created with BioRender.com