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Fig. 6 | Microbiome

Fig. 6

From: Faecalibacterium prausnitzii-derived outer membrane vesicles reprogram gut microbiota metabolism to alleviate Porcine Epidemic Diarrhea Virus infection

Fig. 6

Fp.OMVs alter the metabolic profiles of intestines and cultured bacteria, increasing PC class metabolites. Statistical analysis of differentially upregulated metabolite classes in Limosilactobacillus reuteri (Fp.OMVs group, n = 5; Control group, n = 5) (a), Prevotellamassilia timonensis (Fp.OMVs group, n = 5; Control group, n = 5) (c), and Faecalibacterium prausnitzii (Fp.OMVs group, n = 5; Control group, n = 5) (d) during in vitro culture, as well as in piglet intestines (Fp.OMVs + PEDV group, n = 15; PEDV group, n = 15) (e). b Statistical analysis of the number of downstream products of the top three classes of metabolites in different systems treated with Fp.OMVs. Volcano plot analysis of differentially abundant metabolites in Limosilactobacillus reuteri (f), Prevotellamassilia timonensis (g), Faecalibacterium prausnitzii (h), and piglet intestines (i) after Fp.OMVs pre-treatment. Partial least squares discrimination analysis (PLS-DA) of metabolites in Limosilactobacillus reuteri (j), Prevotellamassilia timonensis (k), Faecalibacterium prausnitzii (l), and piglet intestines (m) after Fp.OMVs pre-treatment. Functional comparative analysis of metabolic components in the KEGG database in Limosilactobacillus reuteri (n), Prevotellamassilia timonensis (o), Faecalibacterium prausnitzii (p), and piglet intestines (q) after Fp.OMVs pre-treatment

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