Fig. 1

CMC exacerbated caerulein-induced AP. a Experimental scheme, mice drink pure water (PW) or CMC solution (1%) for the first 28 days, and on the 28th day, after fasting for 8 h, the mice were given intraperitoneal injections of either normal saline (NS) or caerulein (CAE), respectively. b Pancreas-to-body weight ratio. c Representative images of pancreatic H&E staining. d Histologic score. e Serum amylase. f Serum lipase. g Serum IL-6. h Serum TNF-α. n = 8. *p < 0.05, **p < 0.01 and ***p < 0.001****p < 0.0001. CMC, carboxymethylcellulose; AP, acute pancreatitis