Fig. 3

Fungal proteins associated with bacterial vaginosis (BV) status. A Unsupervised hierarchical clustering was used to group samples based on the log2-transformed imputed intensity-based absolute quantification (iBAQ) values of fungal proteins at visit 1. Red indicates the highest expression, and blue indicates the lowest expression. The darker the red banding pattern, the higher the iBAQ value. The darker the blue banding pattern, the lower the iBAQ value. Samples showed some clustering according to BV status indicated by the top dendrogram. BV status was defined based on Nugent score values. B Principal component analysis (PCA) was used to group individuals based on the log2-transformed imputed iBAQ intensities of fungal proteins for visit 1. Grouping was based on BV status and each point represented an individual women. BV-positive and BV-negative individuals tended to cluster together into their respective groups, with a few outliers. C PCA was used to group individuals based on the log2-transformed imputed iBAQ intensities of fungal proteins for visit 2. Grouping was based on BV status and each point represented individual women. BV-positive and BV-negative individuals tended to cluster together into their respective groups, with a few outliers