Fig. 3

Diet-induced obesity mouse model: systemic effects of Intestinimonas butyriciproducens GL3 (IB). A Body weight gain, shown as the difference in body weight compared to baseline. B Fasting blood glucose levels assessed at the end of the study. C, D Intraperitoneal insulin tolerance test (IPITT): blood glucose levels before and after insulin injection (C) and area under the curve (AUC) of glucose excursion during IPITT (mM*minute) (D). E, F Relative weight of epididymal (eWAT) and inguinal white adipose tissue (iWAT), shown as a percentage of total body weight. Statistical differences between placebo and IB groups were assessed using the non-parametric Mann–Whitney U test. All data are presented as mean values ± SEM (N = 12/group). *P < 0.05