Fig. 1
From: Discovery of robust and highly specific microbiome signatures of non-alcoholic fatty liver disease
Study design overview and structure differences in microbiome among NAFLD and closely associated diseases. A A graphical representation summarizing the cohort information, collected data, and analysis performed in 1206 samples. Detailed criteria on the group formation can be found in the methods section. Created with Biorender.com. B High interconnection between NAFLD-related clinical data and other clinical measures representative of different cardiometabolic diseases. Spearman’s rank-based correlations were used. C Comparison of bacterial species profiles, KEGG pathway profiles, and metabolite profiles among all disease groups adjusted by their respective controls, using non-metric multidimensional scaling (NMDS) of weighted UniFrac, Bray Curtis, and Canberra distances, respectively. The error bars indicate the mean and standard errors of the mean. Significant differences were determined using PERMANOVA and were considered significant if P < 0.05