Fig. 2

Participant fecal sample cultured in the chemostat model generates a bacterial community representative of the donor’s microbiome. Relative abundances of amplicon sequence variants (ASV) that represented bacterial composition were identified by Illumina MiSeq 16S rRNA gene sequencing of fecal samples and of longitudinal chemostat communities cultured from two healthy participants. a, b, c, d Alluvial plots show the relative abundance of ASVs identified on the fecal sample (day 0) and the chemostat cultures inoculated from NS0 (a, b) and NS1 (c, d) individuals, taken over time. ASVs, indicated by colors, are stratified by their identification on the indicated days of culture in the key (upper right). The relative abundance of ASVs from the fecal sample found in the chemostat culture is indicated in brackets adjacent to the day 0 bar. b, d Colors represent the nine predominant phyla. ASVs are ordered by prevalence categories