Fig. 4
Single-nuclei RNA sequencing showed differences in liver cell types among Con, NASH and NASH-T goats. A UMAP plot visualization of seven liver cell types. B Differences in the proportions of liver cell types among the Con, NASH and NASH-T groups. C UMAP plot visualization of eight T-cell subsets. D Differences in the proportions of liver T-cell subsets among the Con, NASH and NASH-T groups. KEGG pathway enrichment of differentially expressed genes among the Con, NASH and NASH-T groups in E TH17 cells and F Treg cells. Con, control group; NASH, nonalcoholic steatohepatitis group; NASH-T, nonalcoholic steatohepatitis tolerance group; Con, control group; NASH, nonalcoholic steatohepatitis group; NASH-T, nonalcoholic steatohepatitis tolerance group