Fig. 3

Overview of the annotations unique to ISS bacteria species. A Venn diagrams showing differences in genes (CD-hit clustering with 40% sequence similarity threshold) found in space isolates compared to their closest terrestrial relatives (ANI provided below each diagram) and the comparison between unique annotations of those genes found in all space isolates. B Overview of grouped annotations, in the form of COG categories, of unique, common-in-all genes derived from CD-Hit two-dimensional clustering. C Structure alignment of novel genes with 52.8% similarity found in both Microbacteria species. Mma, Microbacterium mcarthurae (magenta); Mme, Microbacterium meiriae (orange); pLDDT, predicted local-distance difference test; pTM, predicted template modeling; TM, template modeling, see [26, 27]