Fig. 3
Pseudomonas spp. molecular signatures in BALF samples from CF subjects post-LTx. A Average Pseudomonas abundance among underlying diseases and linear regression over time since LTx. Grey shaded area has 95% confidence interval. B Molecular networks of molecules produced by Pseudomonas spp. identified by GNPS library searching. Each node represents a unique MS/MS spectrum (putative molecule), and connections between nodes are determined by spectral similarity (cosine score) from MS/MS alignment. Pie charts represent total feature abundance colored by the underlying disease. C Linear correlation plot depicting the abundance of SMVFs post-LTx and average abundance of Pseudomonas spp. in CF BALF samples. Dot size denotes Pseudomonas abundance per subject. D Scatter plot of the Pseudomonas SMVFs in CF BALF across years of sampling after LTx and linear regression