Fig. 6

Novel persulfide dioxygenase within CPR bacteria. A Phylogenetic analyses of persulfide dioxygenase proteins from the Alum Rock genomic bins. The blue monophyletic clade shows the persulfide dioxygenase found in CPR bacteria from sulfur-rich environments. B AlphaFold models of Doudnabacterium putative rhodonase (green) and persulfide dioxygenase (blue) aligned with the corresponding domains of the characterized natural fusion protein BpRF (PDB ID: 5VE3). C and D Zoomed views of the active sites of the aligned structures reveal a strong coincidence of the key residues