Fig. 3

Relative abundance of latent and established ARGs divided per gene class and environment. Each gene class is represented by two rows: L for latent and E for established. The labels Birds, Bovines, Mice, Pigs, Humans, and Infants denote metagenomes from the corresponding digestive system. Respiratory system and skin only include human samples. The color intensity reflects the gene- and environment-specific relative abundance, which was calculated based on the median of the relative log-transform abundance over all samples from the environment. To make the genes comparable, all values were normalized based on the environment with the highest abundance. RPG is short for ribosomal protection gene