Fig. 1
From: Multi-omic interactions in the gut of children at the onset of islet autoimmunity
Microbial diversity and abundance are associated with age. The number of OTUs observed and Shannon index related to A age and B case and control status and timepoint. The thick blue curve represents all samples, the grey shaded are represents the 95% confidence interval, and the thinner curves represent the sample group. The first two principal coordinates of the Bray-Curtis distance are shown with each sample colored according to C age, D the proportion of counts attributed to Bacteroidetes, E the proportion of counts attributed to Firmicutes and F case group. Four samples (aged < 1 year of age) with a distinct microbiota are labeled in C. Case pre: IAb+ children prior to seroconversion, case post: IAb+ children after seroconversion, control pre: IAb− controls at first timepoint, control post: IAb− at second timepoint